IASON is a joint project of Tokeya Deep Data Dive GmbH & Co. KG and the chair of clinical psychology and psychotherapy (KliPs) at the Friedrich-Alexander-University (FAU) Erlangen-Nuremberg.

The name “IASON” means “the healer” in Greek and is a heroic figure from Greek mythology.

On the one hand, the IASON project aims to develop a tool for the simple and rapid early diagnosis of Alzheimer's dementia. This tool will be based in particular on the analysis of data from electroencephalography (EEG) and other characteristic data, which are available in significantly altered form in Alzheimer's dementia.

The second focus of the IASON project is the development of an intelligent, emotional-empathetic digital assistant (IEEDA), which supports patients as well as their relatives and nursing staff in communicating with Alzheimer's patients in a variety of sensitive ways.

The IASON project is funded by the Federal Ministry of Education and Research (BMBF), see project description (BMBF), and was selected by the BMBF for the “Project Gallery 2019” alongside 13 other of the funded projects 2019 in the area of “Human-Technology Interaction”.

Note:
In the times of the COVID-19 crisis, the IASON project must also change. We will also make our contribution to support the dementia patients to be cared for in times of the threat of COVID-19! More about this under “The IASON project in times of the COVID-19 crisis”.

Due to the development of the COVID-19 crisis, we feel compelled to publish this project page currently in a temporary transition stage.

The project will undergo some structural changes due to the necessary measures to protect the patients, which can only be reported on at a later date, e.g. after the summer holidays 2020.

For this reason, the individual points of content, particularly with regard to the project structure, objectives and methods used, are only briefly presented here in a concise form and will be updated in a concrete manner at a later date.

 

News

Inrease in funding & Announcement of pilot study

We are very pleased to announce that the BMBF has approved an increase of the funding of the company Tokeya Deep Data Dive GmbH & Co. KG for the financing of the IASON project. The new funds will be used to develop an app combining an automated olfactory and memory test, the two positive results of which allow to predict that people will NOT develop Alzheimer's disease with a probability of 96% within the next 4 years (see “Olfactory test” the study of Devanand et al). The olfactory test will also be used to clarify symptoms of COVID-19 odour loss.

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Loss of sense of smell with COVID-19

The SPIEGEL of 20.8.20 reported on a study on the loss of the sense of smell in COVID-19 diseases, in which the frequency of ACE2 receptors, which are used by the SARS-CoV-2 virus as entry port into the cell, was determined on the basis of human tissue, including the olfactory mucosa.

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Participation in Conference on Alzheimer’s disease

The partners in the joint project IASON participated in the world’s largest conference on Alzheimer’s disease AAIC, which was originally planned to take place in Amsterdam from 27.7.-31.7.20, but which now had to be conducted virtually due to the COVID-19 pandemic. On 28.7.20 the Swedish research group around H. Zetterberg from the University of Gothenburg reported as a world novelty extraordinary progress in the development of blood tests for the very early diagnosis of Alzheimer’s disease.

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Sars-CoV-2 and Alzheimer’s dementia

It is now known that people suffering from COVID-19 temporarily lose their sense of smell and taste. This assumes that the viruses invade the olfactory bulb of the brain (Bulbus olfactorius = BO).

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